Basic studies on delta wing flow modifications by means of apex fences

The effectiveness of apex fences on a 60-deg delta wing at low speeds was experimentally investigated. Resembling highly swept spoilers in appearance, the fences are designed to fold out of the wing apex region upper surface near the leading edges, where they generate a powerful vortex pair. The intense suction of the fence vortices augments lift in the apex region, the resulting positive pitching moment being utilized to trim trailing edge flaps for lift augmentation during approach and landing at relatively low angles of attack. The fences reduce the apex lift at high angles of attack, leading to a desirable nose-down moment. The above projected functions of the apex fence device were validated and quantified through low speed tunnel tests, comprising upper surface pressure surveys on a semispan model and balance measurements on a geometrically similar fully span wing/body configuration. Fence parameters such as area, shape, hinge position and deflection angle were investigated. Typical results are presented indicating the apex fence potential in controlling the longitudinal characteristics of a tail-less delta

More than words: word predictability, prosody, gesture and mouth movements in natural language comprehension

The ecology of human language is face-to-face interaction, comprising cues such as prosody, co-speech gestures and mouth movements. Yet, the multimodal context is usually stripped away in experiments as dominant paradigms focus on linguistic processing only. In two studies we presented video-clips of an actress producing naturalistic passages to participants while recording their electroencephalogram. We quantified multimodal cues (prosody, gestures, mouth movements) and measured their effect on a well-established electroencephalographic marker of processing load in comprehension (N400). We found that brain responses to words were affected by informativeness of co-occurring multimodal cues, indicating that comprehension relies on linguistic and non-linguistic cues. Moreover, they were affected by interactions between the multimodal cues, indicating that the impact of each cue dynamically changes based on the informativeness of other cues. Thus, results show that multimodal cues are integral to comprehension, hence, our theories must move beyond the limited focus on speech and linguistic processing

Electrophysiological signatures of second language multimodal comprehension

Language is multimodal: non-linguistic cues, such as prosody, gestures and mouth movements, are always present in face-to- face communication and interact to support processing. In this paper, we ask whether and how multimodal cues affect L2 processing by recording EEG for highly proficient bilinguals when watching naturalistic materials. For each word, we quantified surprisal and the informativeness of prosody, gestures, and mouth movements. We found that each cue modulates the N400: prosodic accentuation, meaningful gestures, and informative mouth movements all reduce N400. Further, effects of meaningful gestures but not mouth informativeness are enhanced by prosodic accentuation, whereas effects of mouth are enhanced by meaningful gestures but reduced by beat gestures. Compared with L1, L2 participants benefit less from cues and their interactions, except for meaningful gestures and mouth movements. Thus, in real- world language comprehension, L2 comprehenders use multimodal cues just as L1 speakers albeit to a lesser extent

Impact of gastrointestinal side effects on patients’ reported quality of life trajectories after radiotherapy for prostate cancer: Data from the prospective, observational pros-it CNR study

Radiotherapy (RT) represents an important therapeutic option for the treatment of localized prostate cancer. The aim of the current study is to examine trajectories in patients’ reported quality of life (QoL) aspects related to bowel function and bother, considering data from the PROState cancer monitoring in ITaly from the National Research Council (Pros-IT CNR) study, analyzed with growth mixture models. Data for patients who underwent RT, either associated or not associated with androgen deprivation therapy, were considered. QoL outcomes were assessed over a 2-year period from the diagnosis, using the Italian version of the University of California Los Angeles-Prostate Cancer Index (Italian-UCLA-PCI). Three trajectories were identified for the bowel function; having three or more comorbidities and the use of 3D-CRT technique for RT were associated with the worst trajectory (OR = 3.80, 95% CI 2.04–7.08; OR = 2.17, 95% CI 1.22–3.87, respectively). Two trajectories were identified for the bowel bother scores; diabetes and the non-Image guided RT method were associated with being in the worst bowel bother trajectory group (OR = 1.69, 95% CI 1.06–2.67; OR = 2.57, 95% CI 1.70–3.86, respectively). The findings from this study suggest that the absence of comorbidities and the use of intensity modulated RT techniques with image guidance are related with a better tolerance to RT in terms of bowel side effects

Concepts in context: Evidence from a feature-norming study

Concepts are typically conceived as context-free knowledge structures. Recently, a different view has emerged according to which subjects produce situation-specific conceptualizations, thereby raising important questions about the level of contextual dependency in conceptual representations. In this paper, we present a feature-norming study in which subjects are asked to generate properties of concepts presented in context. Collected data are analysed to investigate the actual amount of conceptual variation induced by contexts and the effect of context modality

The effect of incremental context on conceptual processing: evidence from visual world and reading experiments

The analysis of the internal structure of concepts reveals the presence of a substantial amount of contextual information. Even though this interaction is easily recognizable, it is not clear how contextual information is processed and included into concept representations. The aim of this paper is to shed light on this question by analyzing the effect that an increasing amount of context exerts on conceptual processing. We report a self-paced reading experiment and a visual world experiment to test two hypotheses about the integration of context information: the incremental activation hypothesis suggests that the degree of facilitation in concept processing increases with the amount of context available; and the immediate activation hypothesis states that once a sufficient amount of contextual support is reached, no more facilitation occurs. Our data are compatible with the latter account

Utility of Chest Radiographs After Guidewire Exchanges of Central Venous Catheters.

OBJECTIVE: To determine whether chest radiographs are warranted after uncomplicated guidewire exchanges of central venous catheters in patients admitted to a Level I trauma intensive care unit. DESIGN: Prospective study performed in two phases. SETTING: Intensive care unit in a Level I trauma center. PATIENTS: Patients admitted to a Level I trauma center intensive care unit who required central venous catheter guidewire exchanges. INTERVENTIONS: Criteria for uncomplicated guidewire exchanges were established and followed. A catheter exchange checklist was completed at each procedure, and a chest radiograph was performed after each guidewire exchange. The complications followed were catheter malposition, pneumothorax, hemothorax, and cardiac tamponade. Results were reviewed after 3 mos, and a second phase of the study was initiated in which chest radiographs were obtained selectively and were not performed for uncomplicated exchanges. If obtained, subsequent radiographs were reviewed, and patients were followed to discharge for complications. MEASUREMENTS AND MAIN RESULTS: One hundred central venous catheter exchanges with postprocedure radiographs were evaluated in phase I. The only complication identified was one malpositioned catheter. In phase II, 110 patients were followed. Eighty-four patients did not have chest radiographs performed after guidewire exchange; 69 patients had subsequent radiographs documenting good placement of the catheter, and 15 patients did not have a radiograph before death (n = 2) or discharge from the hospital (n = 13). Sixteen patients had postprocedure radiographs performed. There were no malpositioned catheters or complications related to guidewire exchanges. CONCLUSIONS: Chest radiographs are unwarranted after uncomplicated guidewire exchanges of central venous catheters in hemodynamically stable, monitored patients. Eliminating these radiographs will result in significant cost and time savings without adversely affecting patient outcome